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Evaluation of Allergenicity of Genetically Modified Foods

Report of a Joint FAO/WHO Expert Consultation on Allergenicity of Foods Derived from Biotechnology, 22 – 25 January 2001









Last updated date 16/03/2021, see corrigendum



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    Book (series)
    Risk assessment of food allergens
    Part 4: Review and establish exemptions for the food allergens, Meeting report
    2024
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    The Codex Committee on Food Labelling (CCFL) requested scientific advice as to whether certain foods and ingredients, such as highly refined foods and ingredients, that are derived from the list of foods known to cause hypersensitivity can be exempted from mandatory declaration. The objective of this fourth meeting was to expand on the recommendations from the first meeting concerning derivatives of food allergens and establish a framework for evaluating exemptions for food allergens.A pro forma process has been developed and tested against allergen derivatives previously granted exemptions in various countries or regions and found to be effective for consideration in future exemption decisions. The Expert Committee recommends that the process outlined in the pro forma process be used to guide any future development and evaluation of derivative exemptions. Establishment of safety based upon this weight of evidence approach is dependent upon consideration of data quality, outcome of the exposure assessment for all intended ingredient uses (specified for exemption) and review by competent authorities (as needed). When safety is established, exemption can be justified.
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    Book (series)
    Risk Assessment of Food Allergens – Part 5: Review and establish threshold levels for specific tree nuts (Brazil nut, macadamia nut or Queensland nut, pine nut), soy, celery, lupin, mustard, buckwheat and oats
    Meeting report
    2023
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    In Part 2 of the Ad hoc Joint FAO/WHO Expert Consultation on Risk Assessment of Food Allergens, reference doses (RfDs) were recommended for the global priority allergens, which included: walnut (and pecan), cashew (and pistachio), almond, peanut, egg, hazelnut, wheat, fish, shrimp, milk and sesame. Still, RfDs were not recommended for a number of regional or national priority allergens as they did not meet the criteria to be global priority allergens. In an additional request, the Codex Committee on Food Labelling (CCFL) indicated interest in potential RfD derivation for the following specific food allergens: specific tree nuts (Brazil nut, macadamia nut or Queensland nut, pine nut), soy, celery, lupin, mustard, buckwheat, and oats. An overview of the available data and recommended RfDs (or reasons no RfD could be derived) are given here for these specific food allergens. These RfDs were derived following the guidelines described in Part 2 of the Ad hoc Joint FAO/WHO Expert Consultation for deriving an RfD for priority allergenic foods. Details of the available data and discussions of the Expert Committee are presented in this report.
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    Book (stand-alone)
    FAO/WHO Expert Consultation on the Safety Assessment of Foods Derived from Genetically Modified Animals, including Fish
    Rome, 17–21 November 2003
    2004
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    A joint FAO/WHO Expert Consultation on the Safety Assessment of Foods Derived from Genetically Modified Animals, including Fish was held at the Headquarters of the Food and Agriculture Organization of the United Nations (FAO) in Rome from 17 to 21 November 2003. The objective of this Consultation was to provide scientific advice to FAO/WHO and their Member Governments on the safety assessment of foods derived from genetically modified animals, including fish (hereafter “GM animals”). The C onsultation focused on discussing what strategies are appropriate and applicable to the food safety assessment of GM animals. Additionally, it addressed specific issues originating from the production of GM animals as well as environmental and ethical issues. The Consultation did not address all environmental issues but focused on the connection between environmental entry of GM animals and food safety. The Consultation also addressed ethical considerations that relate directly to the scientific assessment of foods derived from GM animals.

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