APPENDIX III. DRAFT MAXIMUM RESIDUE LIMITS FOR VETERINARY DRUGS

(Retained at Step 7 of the Codex Procedure)

NOTE: Section 5 - Reference to JECFA Reports - contains references to the reports of meetings of the Joint FAO/WHO Expert Committee on Food Additives, as published in the WHO Technical Report Series (TRS). Relevant toxicological monographs are published in the WHO Food Additives Series (FAS) and residue monographs of the substances concerned are published in the FAO Food and Nutrition Paper (FNP) Series.

1.Substance: Diminazene

2 Acceptable Daily Intake (ADI) as established by JECFA

0-100 µg/kg body weight

3.1 (a) Commodity:

(a) Muscle (cattle)

(b) MRL:

(b) 500 µg/kg

(c) Definition of residue on which MRL was set:

(c) Diminazene

3.2 (a) Commodity:

(a) Liver (cattle)

(b) MRL:

(b) 12000 µg/kg

(c) Definition of residue on which MRL was set:

(c) Diminazene

3.3 (a) Commodity:

(a) Kidney (cattle)

(b) MRL:

(b) 6000 µg/kg

(c) Definition of residue on which MRL was set:

(c) Diminazene

3.4 (a) Commodity:

(a) Milk (cattle)

(b) MRL:

(b) 150 µg/l (Limit of quantitation of the analytical method)

(c) Definition of residue on which MRL was set:

(c) Diminazene

4. Reference to recommended method(s) of analysis

5. Reference to JECFA Reports:

WHO TRS 788 (1989)
WHO FAS 25 (1990)
FAO FNP 41/2 (1990)
WHO TRS 851 (1995)
WHO FAS 33 (1994)
FAO FNP 41/6 (1994)

6. Reference to previous Codex Reports:

Appendix IV, ALINORM 95/31

1.Substance: Levamisole

2 Acceptable Daily Intake (ADI) as established by JECFA

0-6 µg/kg body weight

3.1 (a) Commodity:

(a) Muscle, kidney and fat (cattle, pigs, sheep, poultry)

(b) MRL:

(b) 10 µg/kg

(c) Definition of residue on which MRL was set:

(c) Levamisole

3.2 (a) Commodity:

(a) Liver (poultry)

(b) MRL:

(b) 100 µg/kg

(c) Definition of residue on which MRL was set:

(c) Levamisole

4. Reference to recommended method(s) of analysis

5. Reference to JECFA Reports:

WHO TRS 799 (1990)
WHO FAS 27 (1991)
FAO FNP 41/3 (1991)
WHO TRS 851 (1995)
WHO FAS 33 (1994)
FAO FNP 41/6 (1994)

6. Reference to previous Codex Reports:

Appendix II, ALINORM 91/31A
Appendix V, ALINORM 93/31A
Appendix II, ALINORM 95/31

1. Substance: Triclabendazole

2 Acceptable Daily Intake (ADI) as established by JECFA

0-3 µg/kg body weight

3.1 (a) Commodity:

(a) Fat (cattle, sheep)

(b) MRL:

(b) 100 µg/kg

(c) Definition of residue on which MRL was set:

(c) 5-Chloro-6-(2',3'-dichlorophenoxy)-benzimidazole-2-

4. Reference to recommended method(s) of analysis

5. Reference to JECFA Reports:

WHO TRS 832(1993)
WHO FAS 31 (1992)
FAO FNP 41/5 (1992)

6. Reference to previous Codex Reports:

Appendix IV, ALINORM 93/31A
Appendix III, ALINORM 95/31

1.Substance: Diminazene
2 Acceptable Daily Intake (ADI) as established by JECFA	0-100 µg/kg body weight
3.1 (a) Commodity:	(a) Muscle (cattle)
(b) MRL:	(b) 500 µg/kg
(c) Definition of residue on which MRL was set:	(c) Diminazene
3.2 (a) Commodity:	(a) Liver (cattle)
(b) MRL:	(b) 12000 µg/kg
(c) Definition of residue on which MRL was set:	(c) Diminazene
3.3 (a) Commodity:	(a) Kidney (cattle)
(b) MRL:	(b) 6000 µg/kg
(c) Definition of residue on which MRL was set:	(c) Diminazene
3.4 (a) Commodity:	(a) Milk (cattle)
(b) MRL:	(b) 150 µg/l (Limit of quantitation of the analytical method)
(c) Definition of residue on which MRL was set:	(c) Diminazene
4. Reference to recommended method(s) of analysis
5. Reference to JECFA Reports:	WHO TRS 788 (1989) WHO FAS 25 (1990) FAO FNP 41/2 (1990) WHO TRS 851 (1995) WHO FAS 33 (1994) FAO FNP 41/6 (1994)
6. Reference to previous Codex Reports:	Appendix IV, ALINORM 95/31

1.Substance: Levamisole
2 Acceptable Daily Intake (ADI) as established by JECFA	0-6 µg/kg body weight
3.1 (a) Commodity:	(a) Muscle, kidney and fat (cattle, pigs, sheep, poultry)
(b) MRL:	(b) 10 µg/kg
(c) Definition of residue on which MRL was set:	(c) Levamisole
3.2 (a) Commodity:	(a) Liver (poultry)
(b) MRL:	(b) 100 µg/kg
(c) Definition of residue on which MRL was set:	(c) Levamisole
4. Reference to recommended method(s) of analysis
5. Reference to JECFA Reports:	WHO TRS 799 (1990) WHO FAS 27 (1991) FAO FNP 41/3 (1991) WHO TRS 851 (1995) WHO FAS 33 (1994) FAO FNP 41/6 (1994)
6. Reference to previous Codex Reports:	Appendix II, ALINORM 91/31A Appendix V, ALINORM 93/31A Appendix II, ALINORM 95/31

1. Substance: Triclabendazole
2 Acceptable Daily Intake (ADI) as established by JECFA	0-3 µg/kg body weight
3.1 (a) Commodity:	(a) Fat (cattle, sheep)
(b) MRL:	(b) 100 µg/kg
(c) Definition of residue on which MRL was set:	(c) 5-Chloro-6-(2',3'-dichlorophenoxy)-benzimidazole-2-
4. Reference to recommended method(s) of analysis
5. Reference to JECFA Reports:	WHO TRS 832(1993) WHO FAS 31 (1992) FAO FNP 41/5 (1992)
6. Reference to previous Codex Reports:	Appendix IV, ALINORM 93/31A Appendix III, ALINORM 95/31