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Development of a protein database and the way forward for reviewing protein requirements

Report of a joint FAO/IAEA technical meeting in Vienna, 10–13 October 2022









FAO & IAEA. 2024. Development of a protein database and the way forward for reviewing protein requirements – Report of a joint FAO/IAEA technical meeting in Vienna, 10–13 October 2022. Rome. 




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    Research approaches and methods for evaluating the protein quality of human foods
    Report of a FAO Expert Working Group, 2 – 5 March 2014, Bangalore, India
    2014
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    Following the 2011 FAO Expert Consultation on dietary protein quality evaluation in human nutrition, a working group was convened in Bangalore, India from 2-5 March 2014 to explore and develop means for producing more data accessible worldwide of ileal amino acid digestibility of human foods, particularly for foods consumed in low income countries. The paucity of data, especially from human studies, remains an obstacle to the practical implementation of the DIASS method for evaluating protein qu ality. The report considers protocols including recommended best practice for pig-based, rat-based and human based assays for true ileal amino acid digestibility determinations to support the generation of new data. The working group considered the development of protocols that would allow non-invasive measures of ileal amino acid digestibility in humans with primary reliance on novel approaches using minimally invasive stable isotopes tracers. Such an exercise would need to involve the determin ation of ileal protein and amino acid digestibility in both humans and animal models to allow the development of robust inter-species protein digestibility predictions.
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    Protein quality assessment in follow-up formula for young children and ready to use therapeutic foods
    Report of the FAO Expert Working Group, Rome, 6–9 November 2017
    2018
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    Consistent with the need to provide safe food for young children, particularly during the complementary feeding period between 12 and 36 months and the period of rapid development to age 59 months, the Food and Agriculture Organization of the United Nations (FAO) convened an Expert Working Group the FAO Headquarters, Rome, Italy, from 6 to 9 November 2017. The meeting addressed questions related to protein quality evaluation in two distinct products used to feed children in different conditions: Ready to Use Therapeutic Food (RUTF) and Follow up Formula for Young Children (FUF-YC). Specific meeting objectives were: • To determine the appropriate comparative protein or amino acid reference pattern to define protein quality for use in FUF-YC and RUTF. • To provide guidance on the preferred protein quality assessment methodology that should be stipulated with the standards for FUF-YC and RUTF. • To provide guidance on the measurement of protein and amino acid digestibility. • To provide the appropriate reference amino acid profiles and the amino acid composition of common ingredients used for FUF-YC and RUTF. • To provide cost implications for countries to use PDCAAS in FUF-YC and RUTF. This report provides future research recommendations including the need to generate data on the true ileal digestibility for different protein sources so that Digestible Indispensable Amino Acid Score (DIAAS) values can be used in the future.
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