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White paper: Antimicrobial resistance in the animal sector in India








Last updated date 12/06/2024, see Corrigendum 


FAO. 2024. White paper: Antimicrobial resistance in the animal sector in India. New Delhi.



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    Antimicrobial resistance (AMR) is a pressing global health concern, jeopardizing decades of medical progress by making once-treatable infections incurable. It occurs when microorganisms no longer respond to antimicrobial treatments, leading to ineffective therapies and heightened disease transmission and mortality rates. The misuse of antimicrobials in humans, animals, and plants exacerbates this issue.In 2019, bacterial resistance to antibiotics caused 1.27 million deaths directly, with numerous others indirectly linked to AMR-related factors. This resistance imposes a substantial economic burden, including prolonged illness, escalated healthcare expenses, and financial strain on patients.The potential consequences of AMR are dire: without effective antimicrobials, modern medicine's ability to combat infections would be severely compromised. Projections indicate that by 2050, AMR could escalate healthcare spending by $1.2 trillion annually and drive millions into extreme poverty. Furthermore, AMR hampers progress towards achieving United Nations Sustainable Development Goals.The spread of resistant bacteria in animals intensifies animal suffering and economic losses, impacting millions dependent on livestock and aquaculture for their livelihoods. Recognizing the crucial role of media in shaping public awareness, the Quadripartite organizations (FAO, UNEP, WHO, and WOAH) prioritize media engagement to raise awareness about AMR. They've developed a practical toolkit to equip stakeholders with resources for media engagement at various levels, facilitating understanding of AMR among policymakers, civil society, and communities. Strategies include engaging target audiences, simplifying messaging, establishing common terminology, and fostering intersectoral coordination in awareness-raising efforts. This toolkit supports engagement with the media on AMR-related issues at all levels, encompassing journalists, bloggers, social media influencers, television and radio producers, online content creators, and community media.
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    Antimicrobials (AM) play a critical role in the treatment of human and animal (aquatic and terrestrial) diseases, which has led to their widespread application and use. Antimicrobial resistance (AMR) is the ability of microorganisms (e.g. bacteria, viruses and some parasites) to stop an antibiotic, such as an antimicrobial, antiviral or antimalarial, from working against them. Globally, about 700 000 deaths per year arise from resistant infections as a result of the fact that antimicrobial drugs have become less effective at killing resistant pathogens. Antimicrobial chemicals that are present in environmental compartments can trigger the development of AMR. These chemicals can also cause antibiotic-resistant bacteria (ARB) to further spread antibiotic resistance genes (ARG) because they may have an evolutionary advantage over non-resistant bacteria. This paper will provide alternative screening methods useful for environmental samples and surveillance approaches in planning such screening efforts. Based on case studies, this paper aims to summarize the current understanding of the occurrence of ARG in the environment, and the antimicrobial movement from agricultural areas to the environment.
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    Antimicrobial resistance (AMR) is now recognized as a major global public health problem which has been aggravated by the irrational use of antimicrobial agents in human and animal health as well as the presence of these agents in the environment. AMR in animal pathogens makes disease treatments ineffective, increases the severity of the disease, reduces productivity and leads to economic losses. In addition, more than half the quantity of antimicrobials used in animals/fish is excreted as waste contaminating soil, water and the environment. This also contributes to the emergence and spread of AMR through selection pressure on microorganisms in the environment. Besides, antimicrobial usage (AMU) can lead to presence of antimicrobial residues in edible animal/fish products which could become a public health risk. Understanding the dynamics of AMR and its surveillance can only be done through quality laboratory services.Laboratory-based surveillance is an integral part of Objective 2 of the National Action Plan of India (2017–2021), which was developed in alignment with the Global Action Plan for AMR.The Indian Council of Agricultural Research (ICAR), with technical assistance from FAO, has established a network of its institutions, the Indian Network for Fishery and Animal Antimicrobial Resistance (INFAAR), to generate nationally representative surveillance data on AMR.

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