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THE USE OF BIOLOGICAL VALUE OF A PROTEIN IN EVALUATING ITS QUALITY FOR HUMAN REQUIREMENTS







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    Research approaches and methods for evaluating the protein quality of human foods
    Report of a FAO Expert Working Group, 2 – 5 March 2014, Bangalore, India
    2014
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    Following the 2011 FAO Expert Consultation on dietary protein quality evaluation in human nutrition, a working group was convened in Bangalore, India from 2-5 March 2014 to explore and develop means for producing more data accessible worldwide of ileal amino acid digestibility of human foods, particularly for foods consumed in low income countries. The paucity of data, especially from human studies, remains an obstacle to the practical implementation of the DIASS method for evaluating protein qu ality. The report considers protocols including recommended best practice for pig-based, rat-based and human based assays for true ileal amino acid digestibility determinations to support the generation of new data. The working group considered the development of protocols that would allow non-invasive measures of ileal amino acid digestibility in humans with primary reliance on novel approaches using minimally invasive stable isotopes tracers. Such an exercise would need to involve the determin ation of ileal protein and amino acid digestibility in both humans and animal models to allow the development of robust inter-species protein digestibility predictions.
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    Development of a protein database and the way forward for reviewing protein requirements
    Report of a joint FAO/IAEA technical meeting in Vienna, 10–13 October 2022
    2024
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    Providing an adequate, sustainable, and nutritious supply of protein remains an increasing challenge in the light of changing food systems and raised levels of food insecurity and malnutrition. A joint FAO and IAEA technical meeting was held in Vienna, in 2022, to discuss the development of a protein quality database and the revision of protein requirements across population groups. Participants updated evidence and related methods on protein requirements and protein quality assessment and designed a framework for the development of a protein digestibility database to aid dialogue on the evaluation of protein quality and protein sufficiency in different populations. The report of this meeting offers a global presentation of the concept of protein quality and requirements throughout the life course. It presents the important elements needed to set protein requirements, such as indispensable amino acid scores and indispensable amino acid reference patterns and the associated methods. The report then narrows down on assessment of protein digestion and metabolic utilization and related assessment methods, including stable isotope tracer techniques. Finally, the report summarizes the framework for a new protein quality database jointly managed by FAO and IAEA, which was agreed on by experts at the technical meeting.The report also recognizes the dearth of data on protein quality from low- and middle-income countries and recommends that resources be mobilized to set up a protein quality database, inclusive of data on climate-smart foods.

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