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Residue Evaluation of Certain Veterinary Drugs. Joint FAO/WHO Expert Committee on Food Additives (JECFA). 70th meeting, 2008. FAO JECFA Monographs 6












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    Residue evaluation of certain veterinary drugs. Joint FAO/WHO Expert Committee on Food Additives (JECFA). 66th meeting 2006 2006
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    The monographs in this volume of the FAO JECFA Monographs on the residues of, statements on, or other parameters of the veterinary drugs on the agenda were prepared by the invited experts for the sixty-sixth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA) held in Rome, Italy, 22-28 February, 2006. This was the seventeenth meeting of JECFA convened specifically to consider residues of veterinary drugs in food animals. The Committee has evaluated residues of veterinary drug s in food animals at the 12th, 26th, 27th, 32nd, 34th, 36th, 38th, 40th, 42nd, 43rd, 45th, 47th, 48th, 50th, 52nd, 54th, 58th, 60th, and 62nd meetings (Ref. 1-15 and 19-22, respectively). The tasks for the Committee were to further elaborate principles for evaluating the safety of residues of veterinary drugs in food and for establishing acceptable daily intakes (ADIs) and recommend maximum residue limits (MRLs) for substances on the agenda when they are administered to food producing animals in accordance with good veterinary practice in the use of veterinary drugs. The enclosed monographs provided the scientific basis for the recommendations of MRLs. There are two significant items in this volume of the FAO JECFA Monographs to bring to the attention of readers. First, this volume is the first in a new format for the presentation of monographs from meetings of the Committee. Second, this was the first meeting of JECFA subsequent to the completion of the workshop to update the principl es and methods of risk assessment for MRLs for pesticides and veterinary drugs, held jointly by FAO/RIVM/WHO, in Bilthoven, The Netherlands, 7 - 11 November, 2005. Specifically, the Committee decided to implement one of the more significant recommendations in the workshop report – the concept of using median residue values to estimate daily intakes of residues of veterinary drugs in food for chronic exposure intake estimates (Ref. 24).
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    Residue Evaluation of Certain Veterinary Drugs - Joint FAO/WHO Expert Committee on Food Additives (JECFA). Meeting 2010 – Evaluation of Data on Ractopamine Residues in Pig Tissues. FAO JECFA Monographs 9 2010
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    This meeting of JECFA, constituted in electronic format from January to May 2010, reviewed data from residue depletion studies of ractopamine hydrochloride in pig tissues, including data from three breeds of pigs in studies undertaken by the People’s Republic of China. The Committee concluded that the MRLs previously recommended are compliant with the ADI as regards consumption of pig tissues of muscle, liver, kidney and fat. Substituting specific organ tissue data for liver and kidney would res ult in dietary intakes that are still below the upper bound of the ADI, with the exception of lung tissue. However, dietary information on consumption off offal and other organ tissue such as lung are lacking and further work should be undertaken to address this issue.
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    Toxicological evaluation of certain veterinary drug residues in food: prepared by the eighty-fifth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA)
    WHO Food Additives Series, No. 76
    2020
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    This volume contains monographs prepared at the eighty-fifth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), which met in Geneva, Switzerland, from 17 to 26 October 2017. The toxicological monographs in this volume summarize data on the veterinary drug residues that were evaluated toxicologically by the Committee: amoxicillin, ampicillin, ethion, flumethrin, halquinol and lufenuron. Annexed to the report is a summary of the Committee’s recommendations on these and other drugs discussed at the eighty-fifth meeting, including acceptable daily intakes (ADIs), acute reference doses (ARfDs) andproposed maximum residue limits (MRLs). This volume and others in the WHO Food Additives Series contain information that is useful to those who produce and use food additives and veterinary drugs and those involved with controlling contaminants in food, government and food regulatory officers, industrial testing laboratories, toxicological laboratories and universities.

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