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Evaluation of certain veterinary drug residues in food: ninety-fourth report of the Joint FAO/WHO Expert Committee on Food Additives

WHO Technical Report Series, no. 1041









Evaluation of certain veterinary drug residues in food: eighty-first report of the Joint FAO/WHO Expert Committee on Food Additives. WHO technical report series No. 1041. World Health Organization and Food and Agriculture Organization of the United Nations, 2022. Licence: CC BY-NC-SA 3.0 IGO.



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    Toxicological evaluation of certain veterinary drug residues in food: prepared by the ninety-fourth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA) 2023
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    This volume contains monographs prepared at the ninety-fourth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), which met in a virtual format, from 16 to 27 May 2022. The toxicological monographs in this volume summarize data on the veterinary drug residues that were evaluated toxicologically by the Committee: imidacloprid and nicarbazin. Annexed to the report is a summary of the Committee’s recommendations on these and other drugs (ivermectin and selamectin) discussed at the ninety-fourth meeting, including acceptable daily intakes (ADIs), acute reference doses (ARfDs) and proposed maximum residue limits (MRLs). This volume and others in the WHO Food Additives Series contain information that is useful to those who produce and use food additives and veterinary drugs, and those involved with controlling contaminants in food, government and food regulatory officers, industrial testing laboratories, toxicological laboratories and universities.
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    Book (stand-alone)
    Evaluation of certain veterinary drug residues in food
    Eighty-eighth report of the Joint FAO/WHO Expert Committee on Food Additives
    2020
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    This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in food and to recommend maximum levels for such residues in food. The first part of the report considers general principles regarding the evaluation of residues of veterinary drugs within the terms of reference of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), including harmonization of residue definition, use of scientific literature in risk assessment, toxicological profiling of compounds and less-than-lifetime dietary exposure assessment, combined exposure to multiple chemicals, and microbiological effects on the safety evaluation of veterinary drug residues in food. Summaries follow the Committee’s evaluations of toxicological and residue data on a variety of veterinary drugs: three insecticides (diflubenzuron, ethion and flumethrin), three antimicrobials (fosfomycin, halquinol and ivermectin) and one antiparasitic agent (selamectin). Annexed to the report is a summary of the Committee’s recommendations on these drugs, including acceptable daily intakes (ADIs) and proposed MRLs.
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    Book (series)
    Residue evaluation of certain veterinary drugs
    Joint FAO/WHO Expert Committee on Food Additives, 94th Meeting (Virtual) 16–27 May 2022
    2023
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    This volume of FAO JECFA Monographs contains residue evaluation of certain veterinary drugs prepared at the 94th Meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), held virtually from 16 to 27 May 2022. The JECFA meeting was specifically convened to consider residues of veterinary drugs in food. The tasks before the Committee were to further elaborate principles for evaluating the safety of residues of veterinary drugs in food, establishing acceptable daily intakes (ADIs) and acute reference doses (ARfDs), and recommending maximum residue limits (MRLs) for such residues when the drugs under consideration are administered to food-producing animals in accordance with good veterinary practice (GVP) in the use of veterinary drugs. The present volume contains monographs on the evaluations of residue data of substances scheduled for evaluation at the request of the Codex Committee on Residues of Veterinary Drugs in Food. A summary of the recommendations on compounds on the agenda and further information required are also presented in this report.

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