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CONSULTATIONS AND WORKSHOPS
WHO/SDE/PHE/FOS/00.6
Original: English
Distr.: Genera
Safety aspects of genetically modified
foods of plant origin
Report of a Joint FAO/WHO Expert Consultation on Foods Derived from Biotechnology
WHO, Headquarters, Geneva, Switzerland
29 May - 2 June 2000
Issued by the World Health Organization in collaboration with the
Food and Agriculture Organization of the United Nations
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FOOD SAFETY PROGRAMME
WORLD HEALTH ORGANIZATION
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This document is available on the Internet at:
http://www.who.int/fsf
Copies may be requested from:
World Health
Organization
Food Safety Programme
CH-1211 Geneva 27
E.mail: [email protected]
Fax: +41 22 791 48 07
© World Health Organization, 2000
This document is not a formal publication of the World Health
Organization (WHO), and all rights are reserved by the Organization. The
document may, however, be freely reviewed, abstracted, reproduced and
translated, in part or in whole, but not for sale nor for use in conjunction
with commercial purposes.
The views expressed in documents by named authors are solely
the responsibility of those authors.
CONTENTS
1. Introduction
2. Background
3. Scope
4. Approaches to the Nutritional and
Food Safety Evaluation of Genetically Modified Foods
4.1 Introduction
4.2 Safety Assessment
4.3 Unintended Effects
4.4 Evaluation of the Concept of
Substantial Equivalence
5. Nutrition-Related Issues
5.1 Introduction
5.2 Unexpected Outcomes: Targeting a
Single Nutrient can Result in Other Alterations
5.3 Methodology for Nutritional and
Safety Evaluation
6. Specific Food Safety Issues
6.1 Introduction
6.2 Gene Transfer from Genetically
Modified Plants: Mechanisms and Consequences for Food Safety
6.3 Allergenicity
7. Conclusions
8. Recommendations
9. References
Annex 1: List of Participants
Annex 2: List of Documents
Annex 3: Reply to the Questions from
the Codex ad hoc Intergovernmental Task Force