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Legislation for veterinary drugs control












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    Joint FAO/WHO Technical Workshop on Residues of Veterinary Drugs without ADI/MRL - Bangkok, 24 – 26 August 2004 2004
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    The Joint FAO/WHO Technical Workshop on Residues of Veterinary Drugs without ADI/MRL met in Bangkok, Thailand from 24th to 26th August 2004, in order to provide FAO, WHO and Codex with a first analysis of disruptions in food trade that occurred in 2001/2002. The disruptions were caused by the detection of trace amounts of chloramphenicol and nitrofurans in animal products. The experts were asked to identify the scientific, technical and regulatory problems related to these findings and to identi fy appropriate follow-up steps. The rapid progress of analytical methods has resulted in large improvements in detection capabilities of low residue levels of veterinary drugs, and has exposed gaps in the current national and international regulatory systems, leading particularly to major impacts on international trade. Decisive and innovative action, which is both realistic and flexible, is needed to address these gaps.
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    Residue evaluation of certain veterinary drugs. Joint FAO/WHO Expert Committee on Food Additives (JECFA). 66th meeting 2006 2006
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    The monographs in this volume of the FAO JECFA Monographs on the residues of, statements on, or other parameters of the veterinary drugs on the agenda were prepared by the invited experts for the sixty-sixth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA) held in Rome, Italy, 22-28 February, 2006. This was the seventeenth meeting of JECFA convened specifically to consider residues of veterinary drugs in food animals. The Committee has evaluated residues of veterinary drug s in food animals at the 12th, 26th, 27th, 32nd, 34th, 36th, 38th, 40th, 42nd, 43rd, 45th, 47th, 48th, 50th, 52nd, 54th, 58th, 60th, and 62nd meetings (Ref. 1-15 and 19-22, respectively). The tasks for the Committee were to further elaborate principles for evaluating the safety of residues of veterinary drugs in food and for establishing acceptable daily intakes (ADIs) and recommend maximum residue limits (MRLs) for substances on the agenda when they are administered to food producing animals in accordance with good veterinary practice in the use of veterinary drugs. The enclosed monographs provided the scientific basis for the recommendations of MRLs. There are two significant items in this volume of the FAO JECFA Monographs to bring to the attention of readers. First, this volume is the first in a new format for the presentation of monographs from meetings of the Committee. Second, this was the first meeting of JECFA subsequent to the completion of the workshop to update the principl es and methods of risk assessment for MRLs for pesticides and veterinary drugs, held jointly by FAO/RIVM/WHO, in Bilthoven, The Netherlands, 7 - 11 November, 2005. Specifically, the Committee decided to implement one of the more significant recommendations in the workshop report – the concept of using median residue values to estimate daily intakes of residues of veterinary drugs in food for chronic exposure intake estimates (Ref. 24).
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    Residue evaluation of certain veterinary drugs
    joint FAO/WHO expert committee on fodd additives, 75th Meeting, Rome, Italy, 8-17 November 2011
    2012
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    This document contains monographs on residue evaluations of certain veterinary drugs, prepared at the seventy-fifth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), which was held in Rome , Italy from 8 to 17 November 2011. Four substances were evaluated for the first time for the animal species concerned - amoxicillin, apramycin, derquantel and monepantel. Three substances were reassessed, monensin, narasin and triclabendzole. Specifically, narasin was reassessed for an analytical method in cattle tissues only and triclabendazole for consideration only of extending the MRLs in sheep to goat tissues. The residue monographs provide information on chemical identity and properties of the compounds, pharmacokinetics and metabolism, residue depletion studies and analytical methods validated and used for the detection and quantification of the compounds. This publication and other documents produced by JECFA contain information that is useful to those who work with or are involved with recommending or controlling maximum residue limits for veterinary drugs in foods of animal origin.

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