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Residue evaluation of certain veterinary drugs

joint FAO/WHO expert committee on fodd additives, 75th Meeting, Rome, Italy, 8-17 November 2011










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    Residue Evaluation of Certain Veterinary Drugs. Joint FAO/WHO Expert Committee on Food Additives (JECFA). 70th meeting, 2008. FAO JECFA Monographs 6 2009
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    This document contains monographs on residue evaluations of certain veterinary drugs, prepared at the seventieh meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), which was held in Geneva, Switzerland from 21 to 29 October 2008. Three substances were evaluated for the first time for the animal species concerned, avilamycin, monensin and narasin. Four substances were reassessed, dexamethasone, tilmicosin, triclabendazole and tylosin. The residue monographs provide informatio n on chemical identity and properties of the compounds, pharmacokinetics and metabolism, residue depletion studies and analytical methods validated and used for the detection and quantification of the compounds. In addition to these monographs, this document includes the considerations and recommendations developed by the Committee for residues of veterinary drugs in honey and possible approaches to derive MRLs for this commodity; and a monograph on residues in aquatic species of and an estimata tion of human dietary exposure to malachite green (an antimicrobial agent and contamimant). This publication and other documents produced by JECFA contain information that is useful to those who work with or are involved with recommending or controlling maximum residue limits for veterinary drugs in foods.
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    Residue evaluation of certain veterinary drugs. Joint FAO/WHO Expert Committee on Food Additives (JECFA). 66th meeting 2006 2006
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    The monographs in this volume of the FAO JECFA Monographs on the residues of, statements on, or other parameters of the veterinary drugs on the agenda were prepared by the invited experts for the sixty-sixth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA) held in Rome, Italy, 22-28 February, 2006. This was the seventeenth meeting of JECFA convened specifically to consider residues of veterinary drugs in food animals. The Committee has evaluated residues of veterinary drug s in food animals at the 12th, 26th, 27th, 32nd, 34th, 36th, 38th, 40th, 42nd, 43rd, 45th, 47th, 48th, 50th, 52nd, 54th, 58th, 60th, and 62nd meetings (Ref. 1-15 and 19-22, respectively). The tasks for the Committee were to further elaborate principles for evaluating the safety of residues of veterinary drugs in food and for establishing acceptable daily intakes (ADIs) and recommend maximum residue limits (MRLs) for substances on the agenda when they are administered to food producing animals in accordance with good veterinary practice in the use of veterinary drugs. The enclosed monographs provided the scientific basis for the recommendations of MRLs. There are two significant items in this volume of the FAO JECFA Monographs to bring to the attention of readers. First, this volume is the first in a new format for the presentation of monographs from meetings of the Committee. Second, this was the first meeting of JECFA subsequent to the completion of the workshop to update the principl es and methods of risk assessment for MRLs for pesticides and veterinary drugs, held jointly by FAO/RIVM/WHO, in Bilthoven, The Netherlands, 7 - 11 November, 2005. Specifically, the Committee decided to implement one of the more significant recommendations in the workshop report – the concept of using median residue values to estimate daily intakes of residues of veterinary drugs in food for chronic exposure intake estimates (Ref. 24).
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    Residue evaluation of certain veterinary drugs
    Joint FAO/WHO Expert Committee on Food Additives - 88th Meeting 2019
    2020
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    This volume of FAO JECFA Monographs contains residue evaluation of certain veterinary drugs prepared at the 88th Meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), held in Rome, 22–31 October 2019. The present meeting was the eighty-eigth in a series of similar meetings. JECFA meeting specifically convened to consider residues of veterinary drugs in food. The tasks before the Committee were to further elaborate principles for evaluating the safety of residues of veterinary drugs in food, establishing acceptable daily intakes (ADIs) and acute reference doses (ARfDs), and recommending maximum residue limits (MRLs) for such residues when the drugs under consideration are administered to food-producing animals in accordance with good practice in the use of veterinary drugs (GVP); to evaluate the safety of residues of certain veterinary drugs; and to respond to specific requests from the Codex Committee on Residues of Veterinary Drugs in Foods (CCRVDF).

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    Report 2022 - Pesticide residues in food
    Joint FAO/WHO Meeting on Pesticide Residues
    2023
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    A Joint Meeting of the Food and Agriculture Organization of the United Nations (FAO) Panel of Experts on Pesticide Residues in Food and the Environment and the World Health Organization (WHO) Core Assessment Group on Pesticide Residues (JMPR) was held in Rome, FAO headquarters, from 13 to 22 September 2022 with FAO pre-meeting from 8 to 12 September 2022. The FAO Panel Members held its pre-meetings in biweekly virtual preparatory sessions from July to September. The WHO Core Assessment Group had organized several preparatory sessions during 2021 and 2022. The Meeting involved 45 participants from five continents spanning most time zones. The Meeting evaluated 47 pesticides and estimated 500 maximum residue limits (MRLs).
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    Développement de l’aquaculture. 4. Une approche écosystémique de l’aquaculture. 2011
    Les dimensions sociales et biophysiques des écosystèmes sont inextricablement liées de telle manière qu’un changement dans une seule dimension est très susceptible de générer un changement dans une autre. Bien que le changement est une conséquence naturelle des interactions complexes, il doit être surveillé et même géré si le taux et la direction du changement risquent de compromettre la résilience du système. “Une approche écosystémique de l’aquaculture (AEA) est une stratégie pou r l’intégration de l’activité dans l’écosystème élargi de telle sorte qu’elle favorise le développement durable, l’équité et la résilience de l’interconnexion des systèmes socio-écologiques.” Etant une stratégie, l’approche écosystémique de l’aquaculture (AEA) n’est pas ce qu’on a fait, mais plutôt comment on l’a fait. La participation des parties intéressées est à la base de la stratégie. L’AEA exige un cadre politique approprié dans lequel la stratégie se développe en plusieurs é tapes: (i) la portée et la définition des limites des écosystèmes et l’identification de la partie intéressée; (ii) l’identification des problèmes principaux; (iii) la hiérarchisation des problèmes; (iv) la définition des objectifs opérationnels; (v) l’élaboration d’un plan de mise en oeuvre; (vi) le processus de mise en oeuvre correspondant qui comprend le renforcement, le suivi et l’évaluation, et (vii) un critique des politiques à long terme. Toutes ces étapes sont informées par les meilleures connaissances disponibles. La mise en oeuvre de l’AEA exigera le renforcement des institutions et des systèmes de gestion associés de sorte qu’une approche intégrée du développement de l’aquaculture peut être mise en oeuvre et compte entièrement des besoins et des impacts d’autres secteurs. La clé sera de développer des institutions capables d’intégration, notamment en fonction des objectifs et des normes convenus. L’adoption généralisée d’une AEA exigera un couplag e plus étroit de la science, la politique et la gestion. Elle exige aussi que les gouvernements incluent l’AEA dans leurs politiques de développement de l’aquaculture, stratégies et plans de développement.
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    Evaluation 2022 part I – Residues. Pesticides residues in food
    Joint FAO/WHO Meeting on Pesticide Residues
    2023
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    A Joint Meeting of the Food and Agriculture Organization of the United Nations (FAO) Panel of experts on Pesticide Residues in Food and the Environment and the World Health Organization (WHO) Core assessment Group on Pesticide Residues (JMPR) was held in Rome, Italy, from 12 to 22 September 2019. The FAO Panel Members met in preparatory sessions from 8 to 12 September.