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DocumentCase study: Escherichia coli O157:H7 in fresh raw ground beef
Background paper for the Joint FAO/WHO expert consultation on the development of risk management strategies based on microbiological risk assessment outputs - Kiel, Germany, 3-7 April 2006
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No results found.During the past ten years, considerable advancements have been achieved in the development of quantitative risk assessments for microbial pathogens in the food supply. More recently, new risk-based management concepts and approaches have been introduced, including the application of food safety objectives (FSOs), performance objectives (POs), and performance criteria (PCs) in order to relate public health goals to the level of stringency required for food safety measures and systems. From these parameters, food safety controls such as process criteria, product criteria and microbiological criteria may be derived. Risk assessments provide the basis for risk-based management options, however, guidelines, methods and practical examples of using risk assessment outputs toward these goals are lacking. -
Book (series)Attributing illness caused by Shiga toxin-producing Escherichia coli (STEC) to specific foods 2019
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No results found.Shiga toxin-producing Escherichia coli (STEC) infections are a substantial public health issue worldwide, causing more than 1 million illnesses, 128 deaths and nearly 13 000 Disability-Adjusted Life Years (DALYs) annually. To appropriately target interventions to prevent STEC infections transmitted through food, it is important to determine the specific types of foods leading to these illnesses. An analysis of data from STEC foodborne outbreak investigations reported globally, and a systematic review and meta-analysis of case-control studies of sporadic STEC infections published for all dates and locations, were conducted. A total of 957 STEC outbreaks from 27 different countries were included in the analysis. Overall, outbreak data identified that 16% (95% UI, 2-17%) of outbreaks were attributed to beef, 15% (95% UI, 2-15%) to produce and 6% (95% UI, 1-6%) to dairy products. The food sources involved in 57% of all outbreaks could not be identified. The attribution proportions were calculated by WHO region and the attribution of specific food commodities varied between geographic regions. In the European and American sub-regions of the WHO, the primary sources of outbreaks were beef and produce. In contrast, produce and dairy were identified as the primary sources of STEC outbreaks in the WHO Western Pacific sub-region. The systematic search of the literature identified useable data from 21 publications of case-control studies of sporadic STEC infections. The results of the meta-analysis identified, overall, beef and meat-unspecified as significant risk factors for STEC infection. Geographic region and age of the study population contributed to significant sources of -
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