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Toxicological evaluation of certain veterinary drug residues in food: prepared by the ninety-fourth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA)









Toxicological evaluation of certain veterinary drug residues in food: prepared by the ninety-fourth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA). Geneva: World Health Organization and Food and Agriculture Organization of the United Nations; 2023 (WHO Food Additives Series, No. 85). Licence: CC BY-NC-SA 3.0 IGO


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    Toxicological evaluation of certain veterinary drug residues in food: prepared by the eighty-fifth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA)
    WHO Food Additives Series, No. 76
    2020
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    This volume contains monographs prepared at the eighty-fifth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), which met in Geneva, Switzerland, from 17 to 26 October 2017. The toxicological monographs in this volume summarize data on the veterinary drug residues that were evaluated toxicologically by the Committee: amoxicillin, ampicillin, ethion, flumethrin, halquinol and lufenuron. Annexed to the report is a summary of the Committee’s recommendations on these and other drugs discussed at the eighty-fifth meeting, including acceptable daily intakes (ADIs), acute reference doses (ARfDs) andproposed maximum residue limits (MRLs). This volume and others in the WHO Food Additives Series contain information that is useful to those who produce and use food additives and veterinary drugs and those involved with controlling contaminants in food, government and food regulatory officers, industrial testing laboratories, toxicological laboratories and universities.
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    Evaluation of certain veterinary drug residues in food: Ninety-eighth report of the Joint FAO/WHO Expert Committee on Food Additives
    WHO Technical Report Series, No. 1055.
    2024
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    This report represents the conclusions of the Joint FAO/WHO Expert Committee on Food Additives (JECFA) convened to evaluate the safety of veterinary drug residues in food: clopidol, imidacloprid and fumagillin. Annexed to this report is a summary of the Committee’s recommendations on these drugs discussed at the ninety-eighth meeting, including acceptable daily intakes (ADIs), acute reference doses (ARfDs), estimated dietary exposure and proposed maximum residue limits (MRLs). Summaries are also provided for general considerations around the matters of interest arising from previous sessions of the Codex Committee on Residues of Veterinary Drugs in Foods (CCRVDF), update of Guidance for the Safety Evaluation of Residues of Veterinary Drugs with incomplete data packages, and release of JECFA Toolbox for Veterinary Drug Residues Risk Assessment.This volume and others in the WHO Technical Report Series contain infrmation that is useful to those who produce and use veterinary drugs, and those involved with controlling contaminants in food, government and food regulatory officers, industrial testing laboratories, toxicological laboratories and universities.
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    Book (stand-alone)
    Evaluation of certain veterinary drug residues in food: ninety-fourth report of the Joint FAO/WHO Expert Committee on Food Additives
    WHO Technical Report Series, no. 1041
    2022
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    This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in food and to recommend maximum levels for such residues in food. The first part of the report considers general principles regarding the evaluation of residues of veterinary drugs within the terms of reference of the Joint FAO/WHO Expert Committee on Food Additives (JECFA). It covers topics such as the parallel review process; estimation of dietary exposure to veterinary drug residues; a risk-based decision tree approach for safety evaluation; assessment of the potential effects of residues on the human intestinal microbiome. Summaries follow the Committee’s evaluations of toxicological and residue data on a variety of veterinary drugs: two antiparasitic agents (imidacloprid, ivermectin) and one coccidiostat (nicarbazin). Additionally, further evaluation of the parasiticide selamectin is included as part of a pilot in support of the proposed parallel review process. Annexed to the report is a summary of the Committee’s recommendations on these drugs, including acceptable daily intakes and proposed maximum residue limits.

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