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Enterobacter sakazakii and other microorganisms in powdered infant formula - Meeting report. Microbiological Risk Assessment Series (MRA) 6













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    Enterobacter sakazakii and Salmonella in Powdered Infant Formula: Meeting Report. Microbiological Risk Assessment Series (MRA) 10 2006
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    The 37th Session of the Codex Committee on Food Hygiene (2005) requested the Food and Agriculture Organization of the United Nations (FAO) and the World Health Organization (WHO) to extend the scientific advice provided by the expert meeting on “Enterobacter sakazakii and other microorganisms in powdered infant formula” held in Geneva in 2004 (FAO/WHO, 2004). Accordingly, a technical meeting was convened on E. sakazakii and Salmonella in powdered infant formula (FAO, Rome, 16-20 January 2006) to consider any new scientific data and to evaluate and apply a quantitative risk assessment model for E. sakazakii in powdered infant formula (PIF). This technical meeting also aimed to provide input to Codex for the revision of the Recommended International Code of Hygienic Practice for Foods for Infants and Children.
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    Enterobacter sakazakii (Cronobacter spp.) in powdered follow-up formula: Meeting Report. Microbiological Risk Assessment Series (MRA) 15 2008
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    E. sakazakii (Cronobacter spp.) is a Gram-negative, motile, peritrichous non-spore forming, facultative anaerobic bacterium. It is an opportunistic pathogen and has been linked with serious infections in infants (FAO/WHO, 2004, 2006; Mullane et al., 2007a), notably following the consumption of PIF. Often described as an emerging pathogen, E. sakazakii (Cronobacter spp.) can cause bacteraemia and meningitis in infants and has also been isolated from infants in association with necrotizi ng enterocolitis (NEC). The first cases attributed to this organism occurred in 1958 in England (Urmenyi and Franklin, 1961). Since then and up to July 2008, the meeting has identified around 120 documented cases of E. sakazakii infection and at least 27 deaths from all parts of the world, in the published literature and in reports submitted by public health organizations and laboratories (Annex 1).
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