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Rift Valley Fever (RVF) vaccine development, progress and constraints








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    Rift Valley Fever (RVF) vaccine development, progress and constraints 2011
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    International workshop - list of participants
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    International workshop - agenda
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    Rift Valley fever vaccine development, progress and constraints
    GF-TADs meeting / November 2010
    2011
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    Rift Valley fever (RVF) is an acute arthropod-borne infection first recognized in Kenya in 1931. Today, the RVF virus has been found in countries across Africa, the Arabian Peninsula and islands in the Indian Ocean, including Madagascar, Comores and Mayotte. This virus has a strong capacity to spread to previously unaffected areas, thanks to its broad host range and ability to be transmitted by at least 30 different mosquito species ¿some of which are found in Europe, Australasia and the America s. Outbreaks following first incursions of RVF can result in explosive epidemics involving both humans and livestock.The control of RVF outbreaks includes vaccination of susceptible animals. Two vaccines are currently available; however, each has significant drawbacks. There is a widely recognized need to develop safer and more efficacious vaccines for animals. Rift Valley fever vaccine development, progress and constraints is the report of an international expert workshop that brought together leading experts and policy-makers in RVF virology, epidemiology and vaccine development. The workshop objective was to gain consensus and make recommendations on the desired features of novel veterinary RVF virus vaccines, and to explore how incentives can be established to assure that these vaccines come to market.

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