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Strategic Framework for collaboration on antimicrobial resistance

Together for One Health









This is a co-published publication, read this book also on WHO's webpage


WHO, FAO, OIE, UNEP. Strategic framework for collaboration on antimicrobial resistance – together for One Health. Geneva: World Health Organization, Food and Agriculture Organization of the United Nations and World Organization for Animal Health; 2022.



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    Evaluation of FAO’s role and work on antimicrobial resistance (AMR) 2021
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    Antimicrobial resistance (AMR) is the ability of microorganisms to fight antimicrobial compounds, reducing the efficacy of treating diseases in humans, animals, and plants. AMR risk is outpacing human population growth, owing to misuse of antimicrobials in large quantities in food systems, and is a serious threat to food security and sustainable development. FAO, with the World Health Organization (WHO), the World Organization for Animal Health (OIE), and the United Nations Environment Programme (UNEP), is supporting countries in developing and implementing their One Health National Action Plans on AMR. The eventual aim is to ensure sustainable use of antimicrobials to minimize AMR risks, in alignment with the Global Action Plan on AMR. The scope of the evaluation covers FAO’s entire work on AMR up to early 2020 and its role in the global AMR architecture. It examines FAO’s organizational and institutional set-up for AMR work. FAO has a strong mandate to work on AMR, implementing activities in 45 countries and providing far-reaching support on AMR National Action Plans (NAPs). FAO’s technical expertise is a key comparative advantage in its work on AMR. It is underpinned by the strong scientific grounding of FAO’s work, engendered in its AMR working groups and supported by its collaboration with research centers, universities, and the Tripartite organizations. Nevertheless, the work is relatively recent and, given the long impact pathways, it has had limited results. A comprehensive strategic and programmatic approach would increase the likelihood of achieving results in combating AMR. FAO should prioritize its work in a long-term strategy on AMR that recognizes the seriousness of the threat and is fully integrated into the Organization’s Strategic Framework. The strategy should set out FAO’s long-term role in combating AMR and that of its divisions and offices, as well as its approach at the country and regional level. FAO should consolidate its work on AMR through a strong programmatic approach with a central coordination and management structure that links with the Regional Offices and is supported by dedicated core funding.
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    Antimicrobial Resistance Multi-Partner Trust Fund annual report 2021 2022
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    Antimicrobial resistance (AMR) is a major global threat to humans, animals, plants, food systems and the environment. Without investment and commitments from countries globally to address this challenge, AMR will continue unabated. The Antimicrobial Resistance Multi-Partner Trust Fund (AMR MPTF) has successfully begun the essential work to address this challenge. With the overall goal of “having reduced levels of AMR and slower development of resistance” in 10 years’ time, the AMR MPTF has seen, in 2021, the initial steps towards this goal, with capacity built in 8 countries, and coordinated steppingstones under the global programme. Despite continuous restrictions caused by the coronavirus disease 2019 (COVID-19) pandemic, throughout 2021 collaboration between the Quadripartite organizations – the Food and Agriculture Organization of the United Nations (FAO), the World Organisation for Animal Health (OIE), the United Nations Environment Programme (UNEP) and the World Health Organization (WHO) – sustained strong implementation progress at global, regional and country level. Progress against the overarching AMR MPTF results matrix is now being reported for the first time. This was possible through the financial partnership of the Governments of Netherlands, the United Kingdom (using UK aid funding through the Fleming Fund), Sweden (including through the Swedish International Development Cooperation Agency – Sida) as well as Germany (through the German Agency for International Cooperation – GIZ).
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    Evaluation of the One Health (Better Production 3) programme
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    In November 2022, the Programme Committee endorsed the Office of Evaluation (OED)’s work plan of evaluations 2022–2025, which included an evaluation of FAO’s Programme Priority Area on One Health (Better Production 3). This Programme Priority Area (Better Production 3), created under the Strategic Framework 2022–2031 has its roots in FAO’s decades-long work on issues related to One Health.In April 2010, FAO authored A Tripartite Concept Note, together with the World Health Organization (WHO) and the World Organisation for Animal Health (WOAH, former OIE), on “Sharing responsibilities and coordinating global activities to address health risks at the animalhuman- ecosystems interfaces”, and thus creating the Tripartite on One Health. In 2021, the United Nations Environment Programme (UNEP) joined and expanded the international collaboration into the Quadripartite. In May 2021, the One Health High-Level Expert Panel (OHHLEP) was launched to provide the Quadripartite with evidencebased scientific and policy advice to address the challenges raised at the animal-human-environment interface using the One Health approach.

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