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Dromedary camels and MERS-CoV: Filling knowledge gaps














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    Brochure, flyer, fact-sheet
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    Investigating potential recombination of MERS-CoV and SARS-CoV-2 or other coronaviruses in camels
    Supplementary recommendations for the epidemiological investigation of SARS-CoV-2 in exposed animals
    2021
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    Dromedary camels are the main reservoir for Middle East Respiratory Syndrome Coronavirus (MERS-CoV). Genetic analysis of MERS-CoV isolates from humans and dromedaries revealed that direction of transmission is from camels to humans. Furthermore, several studies reported evidence of camel infection by other human CoVs, animal CoVs or unknown coronaviruses. There is evidence of recombination between different betacoronaviruses in camels. Analysis of the Angiotensin converting enzyme 2 receptor (ACE2) binding in dromedaries predicted potential binding affinity to the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) receptor binding domain (RBD), however some other studies predicted the contrary. With the pandemic spread of SARS-CoV-2, it is not a matter of if but rather when camels will be exposed to SARS-CoV-2 in these countries. Co-circulation of both viruses in the same host can favour virus recombination, and may lead to increased virulence in animals and/or humans if the recombinant virus incorporates pathogenicity of MERS-CoV with the transmissibility of SARS-CoV-2. Further investigations into camel susceptibility to SARS-CoV-2, the possibility for recombination between MERS-CoV and SARS-CoV-2 or other coronaviruses in camels, and the associated zoonotic potential are therefore urgently required to ensure early-detection of such events.
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    Book (series)
    Technical study
    Swab and tissue sample collection procedures enhancing MERS-CoV detection in camels
    An illustrative guideline
    2019
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    Dromedary camels are thought to be the natural reservoir of MERS-CoV and can be a source of infection for humans. This document provides simplified guidelines on good practices to reach the turbinate respiratory epithelium in live and slaughtered camels with the aim of collecting high quality samples in order to enhance MERS-CoV detection, isolation and characterization; in addition, common errors and biosecurity flaws that affects the RT-PCR results are described. The manuscript will be the first document to provide practical illustrated guidance on how to collect high quality samples from the nasal turbinate of camels for the purpose of MERS-CoV detection.
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    Book (series)
    Technical report
    Global technical meeting on MERS-CoV and other emerging zoonotic coronaviruses
    Virtual meeting, 15–16 November 2021
    2022
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    Over the last nine years, FAO, WHO and WOAH have worked with Member States, public health professionals and experts across multiple sectors and technical disciplines to improve preparedness and response capacities for MERS-CoV and other high threat zoonotic pathogens around the world. This work continues to bring together public health and animal health experts from affected and at-risk countries, scientists, and subject matter experts of high threat respiratory pathogens to review the latest scientific evidence on MERS-CoV and improve multi-sectoral collaboration. As a follow-up to previous technical meetings on MERS-CoV hosted by FAO, WHO and WOAH, a Global Technical Meeting was convened virtually on 15-16 November 2021 to share the latest findings from accelerated efforts to implement the MERS-CoV public health research agenda and research and development (R&D) road map, in the context of the ongoing COVID-19 pandemic. This documents presents a summary of the presentations and discussions.

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    The FAOSTAT emissions database is composed of several data domains covering the categories of the IPCC Agriculture, Forestry and Other Land Use (AFOLU) sector of the national GHG inventory. Energy use in agriculture is additionally included as relevant to emissions from agriculture as an economic production sector under the ISIC A statistical classification, though recognizing that, in terms of IPCC, they are instead part of the Energy sector of the national GHG inventory. FAO emissions estimates are available over the period 1961–2018 for agriculture production processes from crop and livestock activities. Land use emissions and removals are generally available only for the period 1990–2019. This analytical brief focuses on overall trends over the period 2000–2018.
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    The State of Food Security and Nutrition in the World 2021
    Transforming food systems for food security, improved nutrition and affordable healthy diets for all
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    In recent years, several major drivers have put the world off track to ending world hunger and malnutrition in all its forms by 2030. The challenges have grown with the COVID-19 pandemic and related containment measures. This report presents the first global assessment of food insecurity and malnutrition for 2020 and offers some indication of what hunger might look like by 2030 in a scenario further complicated by the enduring effects of the COVID-19 pandemic. It also includes new estimates of the cost and affordability of healthy diets, which provide an important link between the food security and nutrition indicators and the analysis of their trends. Altogether, the report highlights the need for a deeper reflection on how to better address the global food security and nutrition situation.To understand how hunger and malnutrition have reached these critical levels, this report draws on the analyses of the past four editions, which have produced a vast, evidence-based body of knowledge of the major drivers behind the recent changes in food security and nutrition. These drivers, which are increasing in frequency and intensity, include conflicts, climate variability and extremes, and economic slowdowns and downturns – all exacerbated by the underlying causes of poverty and very high and persistent levels of inequality. In addition, millions of people around the world suffer from food insecurity and different forms of malnutrition because they cannot afford the cost of healthy diets. From a synthesized understanding of this knowledge, updates and additional analyses are generated to create a holistic view of the combined effects of these drivers, both on each other and on food systems, and how they negatively affect food security and nutrition around the world.In turn, the evidence informs an in-depth look at how to move from silo solutions to integrated food systems solutions. In this regard, the report proposes transformative pathways that specifically address the challenges posed by the major drivers, also highlighting the types of policy and investment portfolios required to transform food systems for food security, improved nutrition, and affordable healthy diets for all. The report observes that, while the pandemic has caused major setbacks, there is much to be learned from the vulnerabilities and inequalities it has laid bare. If taken to heart, these new insights and wisdom can help get the world back on track towards the goal of ending hunger, food insecurity, and malnutrition in all its forms.