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MeetingL'ESB, urgence sanitaire nationale et transfrontière 2002Une nouvelle maladie du bétail, l'encéphalopathie spongiforme bovine (ESB) a été décelée pour la première fois en 1986. Elle appartient au groupe des encéphalopathies spongiformes transmissibles (EST). A l'origine, on ignorait à l'origine que l'agent infectieux de l'ESB pouvait contaminer les êtres humains, mais il est maintenant établi que l'ESB, et une variante humaine d'encéphalopathie spongiforme transmissible, la maladie de Creutzfeldt-Jacob, sont provoquées par le même agent infectieux. Ce s maladies sont toujours mortelles. L'agent qui provoque l'ESB est extrêmement résistant et n'est pas éliminé par les mesures qui tuent normalement les agents infectieux (bactéries, virus), notamment la cuisson. Les règles d'hygiène courantes sont donc sans effet pour lutter contre l'ESB; le seul moyen de protéger la santé humaine est d'éliminer l'agent infectieux de la chaîne alimentaire.
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No Thumbnail AvailableBook (series)Manual on Bovine Spongiform Encephalopathy 1998
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No results found.Bovine spongiform encephalopathy (BSE) was first recognized and defined as a pathological entity in the United Kingdom in November 1986 (Wells et al., 1996). Initial epidemiological investigations and examination of archived brains indicated that the first cases occurred around April 1985. Subsequently, the largest freeborn epidemic of a transmissible spongiform encephalopathy (TSE) occurred which has had severe economic effects and has caused concern for public health. The initial clinical signs of this fatal neurological disease are non-specific, typically involving behavioural changes. As the clinical phase progresses the disease is typified by alterations in mental state and of sensation and ataxia. The majority of affected animals reach the advanced stages within two to three months from the onset, when slaughter on welfare grounds becomes necessary (Wilesmith et al., 1988). The disease affects adult animals, with a peak age at onset of four to five years of age. Both se xes and all breeds are equally susceptible. BSE can only be confirmed post-mortem by pathological examination of brain tissue. Histological examination of the hind brain has been the primary method for the statutory diagnosis in the United Kingdom (Wells et al., 1989). The histological changes are typical of the TSEs. Microscopic lesions in the central nervous system consist of bilaterally symmetrical, non inflammatory vacuolation of neuronal perikarya and grey matter neuropil. BSE is transmissible by parenteral inoculation of inbred strains of mice (Fraser et al., 1988) and cattle (Dawson, Wells and Parker, 1990). In cattle the incubation period is approximately 18 months using brain homogenates from natural terminal cases. -
MeetingFAO Veterinary Public Health and Food and Feed Safety Programme: the Safety of Animal Products from Farm to Fork 2002
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No results found.The livestock sector plays an essential role in agricultural and economic development as well as in food security. Public concern about the safety of foods of animal origin has recently heightened due to problems that have arisen with outbreaks of food-borne infections (BSE, E.coli, Salmonella, Campylobacter, Listeria, etc.) and chemical contamination (pesticides, heavy metals, dioxins), as well as due to growing concerns about veterinary drug residues and microbial resistance to antibiotics. Th ese problems have drawn attention to the production practices within the livestock industry and have prompted health professionals and the food industry to closely scrutinise quality and safety problems that can arise in foods of animal origin. In addition to national food safety, these issues have serious implications for international trade in livestock products and animal feed.
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