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Preventing E. coli in Food







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    Book (series)
    Enterohaemorrhagic Escherichia coli in Raw Beef and Beef Products: Approaches for the Provision of Scientific Advice. Microbiological Risk Assessment Series (MRA) 18 2011
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    The specific objectives of the meeting were to: • Review the existing risk assessments on EHEC in terms of (a) their fulfilling their scope and providing the basis for scientifically-based risk-management actions; and (b) their potential application (in whole or on a modular basis) to the development of a risk assessment at the international level. • Consider the risk management actions, if any, taken to date that were based on risk assessment and identify the strengths and weakness of the risk assessments from a risk management perspective, in particular identifying when and why the risk assessments did not meet the needs of risk managers. • Identify the key issues currently faced by risk managers in terms of addressing the problems associated with EHEC in raw beef and beef products. Considering the output of the above objectives and the existing data on EHEC in raw beef and beef products, provide guidance to FAO and WHO on the specific areas to be addressed in any future work on this issue, and how to address them.
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    The Use of Microbiological Risk Assessment Outputs to Develop Practical Risk Management Strategies: Metrics to improve food safety
    Report
    2006
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    In 2004 FAO and WHO agreed that more work was needed in this area and this was endorsed by the Codex Committee on Food Hygiene. FAO and WHO then initiated a programme of activities to address this, with the ultimate objective of providing guidance in the application of MRA to establish specific numerical targets or standards. These activities have included the establishment of a number of working groups to look at the issues and the results of microbiological risk assessment to develop food cont rol measures, with particular emphasis on the establishment of targets or metrics and their application. The outputs of these working groups and other relevant documentation were then considered and discussed by an expert meeting convened in Kiel, Germany on 3 – 7 April 2006. This report aims to summarise the recent international discussions and their outcomes and provide an overview as to the current status in terms of the application of MRA in food safety management. Although good progress has been made in recent years, many challenges remain.
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    Shiga toxin-producing Escherichia coli (STEC) and food: attribution, characterization, and monitoring
    Meeting Report
    2018
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    Shiga toxin-producing Escherichia coli (STEC) infections are a substantial health issue worldwide. Circa 2010, foodborne STEC caused > 1 million human illnesses, 128 deaths, and ~ 13,000 Disability Adjusted Life Years (DALYs). Targeting interventions appropriately relies on identifying those strains of greatest risk to human health and determining the types of foods that cause STEC infections. There are hundreds of STEC serotypes; however, based on the evidence gathered during the review, the Expert Group concluded that the serotype of the STEC strain should not be considered a virulence criterion. All STEC strains with the same serotype should not be assumed to carry the same virulence genes and to pose the same risk, as many STEC virulence genes are mobile and can be lost or transferred to other bacteria. this report proposes a set of criteria for categorizing the potential risk of severity of illness associated with a STEC in food is recommended based on evidence of virulence gene profiles and associations with clinical severity. The criteria could be applied by risk managers in a risk-based management approach to control STEC in food. While ruminants and, other land animals are considered the main reservoirs for STEC, various largescale outbreaks have been linked to other foods. Thus, the report also addresses source attribution of foodborne STEC infections globally in order to inform the development of international standards by the Codex Alimentarius on the control of STEC, and in particular identify the foods which should be the focus of those standards. Finally it provides a review of monitoring programmes and methodology for STEC which can serve as a reference for countries planning to develop such programmes.

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