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FAO/WHO Expert Consultation on the Safety Assessment of Foods Derived from Genetically Modified Animals, including Fish

Rome, 17–21 November 2003












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    FAO/WHO Expert Consultation on the Safety Assessment of Foods Derived from Recombinant-DNA Animals. Report
    Geneva, Switzerland, 26 February – 2 March 2007
    2007
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    A joint FAO/WHO Expert Consultation on the Safety Assessment of Foods Derived from Recombinant-DNA Animals was held at the Headquarters of the World Health Organization (WHO) in Geneva from 26 February to 2 March 2007. The objective was to provide scientific advice to FAO/WHO and their Member States on two sets of questions regarding: i) marker and reporter genes; and ii) non-heritable applications. The Codex ad hoc Intergovernmental Task Force on Foods Derived from Biotechnology had specificall y requested advice on these questions. This Consultation built upon the conclusions and recommendations from the Joint FAO/WHO Expert Consultation on the Safety Assessment of Foods Derived from Genetically Modified Animals, including Fish (FAO/WHO 2004). A variety of reporter and selectable marker genes are used extensively in plants and laboratory animals and are now being used in food animals. Few non-antibiotic resistance marker and reporter genes are currently used for producing recombinant- DNA animals intended for food and no studies are available on their food safety. It would be desirable to develop new selectable marker genes that do not confer antibiotic resistance.
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    Safety assessment of foods derived from genetically modified microorganisms
    Report of a Joint FAO/WHO Expert Consultation on Foods Derived from Biotechnology, WHO Headquarters, Geneva, Switzerland, 24 – 28 September 2001
    2001
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    A Joint FAO/WHO Expert Consultation on Foods Derived from Biotechnology – Safety Assessment of Foods Derived from Genetically Modified Microorganisms (GMMs) was held at the Headquarters of the World Health Organization (WHO) in Geneva from 24 – 28 September 2001. A total of 27 experts, including authors of discussion papers, participated in the Consultation. Ms Ann Kern, Executive Director, Cluster of Sustainable Development and Healthy Environments, opened the Consultation on behalf of Di rectors-General of WHO and the Food and Agriculture Organization of the United Nations (FAO). Ms Kern stated that WHO and FAO have been organizing Consultations of this kind since 1990 to provide scientific and technical guidance to Member States and to the Codex Alimentarius Commission. Ms Kern also expressed the appreciation of the two Organizations to the Government of Japan for its generosity in supplying additional funding for this Consultation. She acknowledged the interest of Me mber States in these sometimes hotly debated issues, and the need for sound scientific advice developed and formulated by the Expert Consultations upon which Governments can base their discussions. Clear assessment and communication of scientific data is becoming increasingly important so that the scientific risk assessment process is accurately reflected in the risk management process. Ms Kern suggested that the issues of safety and nutritional assessment of foods derived from biote chnology would be even more important in the near future with the rapid development of new foods with potential benefits related to health.
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    Evaluation of Allergenicity of Genetically Modified Foods
    Report of a Joint FAO/WHO Expert Consultation on Allergenicity of Foods Derived from Biotechnology, 22 – 25 January 2001
    2001
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    Scope: The Consultation was convened to provide FAO, WHO and their Member States with scientific advice in relation to the assessment of allergenicity in genetically modified foods. This would cover in particular: General consideration of allergenicity of genetically modified foods consideration of allergenicity specifically relevant to genetically modified foods Consideration of the decision-tree approach consideration and possible revision of the decision-tree for the ass essment of allergenicity of genetically modified foods developed preliminarily by the June 2000 Joint FAO/WHO Consultation on Foods Derived from Biotechnology development of standardised procedures for consideration of the use of individual criteria used in the decision tree, with a view to a harmonised application of the decision-tree consideration of the possibility of post market surveillance for inclusion in the decision-tree and technologies supporting the implementation of post market surveillance. Specific questions arising in relation to the assessment of allergenicity of genetically modified foods use of databases in the assessment of allergenicity of genetically modified foods use of animal testing other related issues

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