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Microbiome: The missing link?

Science and innovation for health, climate and sustainable food systems










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    Book (series)
    The impact of veterinary drug residues on the gut microbiome and human health
    A food safety perspective
    2023
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    With a food safety focus, a scientific literature review was conducted to characterize the current understanding about the effects of veterinary drug residues on the human gut microbiome and potential implications on human health and non-communicable diseases (NCDs). The main aspects analysed are (1) effects of individual or combined drugs on the composition, diversity and function of gut microbiome using in vivo or in vitro models; (2) health implications resulting from the veterinary drug-microbiome interactions and underlying mechanisms; (3) establishment of causality; and (4) influence of the gut microbiome on the metabolism and bioavailability of veterinary drugs. The research was also scoped to identify current gaps, limitations and needs for the eventual consideration of microbiome-related data in chemical risk assessment. With this work, ESF contributes to the FAO global programme on the impact of food systems on NCDs and obesity, by understanding the potential health implications of gut microbiome-veterinary drug interactions. The outcomes will provide information which can be used to improve nutritional strategies and food safety policies.
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    Book (series)
    The impact of pesticide residues on the gut microbiome and human health
    A food safety perspective
    2023
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    With a food safety focus, a scientific literature review was conducted to characterize the current understanding about the effects of pesticide residues on the human gut microbiome and potential implications on human health and non-communicable diseases (NCDs). The main aspects analysed are (1) effects of individual or combined pesticides on the composition, diversity and function of gut microbiome using in vivo or in vitro models; (2) health implications resulting from the pesticide-microbiome interactions and underlying mechanisms; (3) establishment of causality; and (4) influence of the gut microbiome on the metabolism and bioavailability of pesticides. The research was also scoped to identify current gaps, limitations and needs for the eventual consideration of microbiome-related data in chemical risk assessment. With this work, ESF contributes to the FAO global programme on the impact of food systems on NCDs and obesity, by understanding the potential health implications of gut microbiome-pesticide interactions. The outcomes will provide information which can be used to improve nutritional strategies and food safety policies.
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    Book (series)
    The impact of microplastics on the gut microbiome and health
    A food safety perspective
    2023
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    With a food safety focus, a scientific literature review was conducted to characterize the current understanding about the effects of microplastics on the gut microbiome and potential health implications. The main aspects analysed are (1) the effects of microplastics on the composition, diversity and function of gut microbiome using in vito and in vivo models; (2) health implications resulting from the microplastic–microbiome interactions and underlying mechanisms; (3) the establishment of causality; and (4) influence of the gut microbiome on microplastic biodegradation. The research was also scoped to identify current gaps, limitations and needs for the eventual consideration of microbiome-related data in chemical risk assessment. With this work, ESF contributes to the FAO global programme on the impact of food systems on NCDs and obesity, by understanding the potential health implications of gut microbiome–microplastic interactions. The outcomes will provide information which can be used to improve food safety policies.

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